General Western Blot Reagents
Abcam PMSF, protease inhibitor, 100G
MW 174.19 Da, Purity >98%. Non-specific protease inhibitor; binds key active site serine residue in serine proteases, acetylcholinesterases, and thiol proteases. Suitable for use in vitro; in the preparation of cell lysates, and in vivo where it has been shown to block anandamide (ab120429) metabolism. Able to rapidly cross the BBB.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Metho x y- x 04, amyloid beta fluorescent marker, 25MG
MW 344.4 Da, Purity >98%. Blood-brain barrier permeable amyloid β fluorescent marker. Blue fluorophore. Derivative of Congo Red (ab145645) and Chrysamine G. Selectively binds fibrillar β-sheet deposits with high affinity (Ki = 26.8 nM). Detects plaques, tangles and cerebrovascular amyloid in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam E-4031 dihydrochloride, HERG K+ channel blocker, 5MG
MW 474.4 Da, Purity >99%. Type III antiarrhythmic drug that blocks ion channels encoded by the ether-a-go-go related gene (ERG1 or KCNH1). Blocks channels in the open configuration with little effect on the channels in the closed configuration. The IC50 for block of human ERG channels in expression systems is approx. 350 nM.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Clioquinol, Metal chelator and ionophore, 1G
MW 305.5 Da, Purity >97%. Metal chelator and ionophore with beneficial effects in animal models of neurodegenerative diseases (Alzheimer's, Parkinson's and Huntington's disease). Effects on Alzheimer's disease attributed to copper and zinc chelation or increased level of a metalloprotease. Other actions reported including iron chelation, inhibition of Huntington expression from its mRNA, proteasome inhibition when complexed with copper, and stimulation of tumor necrosis factor-α secretion. Also inhibitor of CLK-1/MCLK1 (an aging-associated protein).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Histone H4 peptide, 1MG
Human Histone H4 peptide is a Synthetic blocking peptide. >90% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: H4/A, H4FA, HIST1H4A, H4C2, H4/I, H4FI, HIST1H4B, H4C3, H4/G, H4FG, HIST1H4C, H4C4, H4/B, H4FB, HIST1H4D, H4C5, H4/J, H4FJ, HIST1H4E, H4C6, H4/C, H4FC, HIST1H4F, H4C8, H4/H, H4FH, HIST1H4H, H4C9, H4/M, H4FM, HIST1H4I, H4C11, H4/E, H4FE, HIST1H4J, H4C12, H4/D, H4FD, HIST1H4K, H4C13, H4/K, H4FK, HIST1H4L, H4C14, H4/N, H4F2, H4FN, HIST2H4, HIST2H4A, H4C15, H4/O, H4FO, HIST2H4B, H4C16, H4-16, HIST4H4, H4C1, Histone H4, H4K8cr
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam Crystal violet, Cation-based violet dye, 25G
MW 408 Da. Cation-based violet dye. Interacts with aqueous KI - I₂ during Gram staining to produce a precipitate. Histological stain for Gram-positive bacteria and DNA. Shows antibacterial, antifungal, and anthelmintic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Concanamycin C, H+-ATPase inhibitor, 100UG
MW 823.1 Da, Purity >98%. Potent, selective vacuolar-type H+-ATPase inhibitor. Macrolide antibiotic agent. Concanamycin A (ab144227) analog. Shows antiproliferative and potent antifungal effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Fluconazole, Cytochrome P450 inhibitor, 50MG
MW 306.27 Da, Purity >99%. Triazole antifungal agent. Cytochrome P450 inhibitor (IC₅₀ values are 30.3, 12.3, 13.1 μM for CYP2C9, CYP2C19 and CYP3A4, respectively). Penetrates the blood-brain barrier.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DPN, ERbeta agonist, 50MG
MW 239.27 Da, Purity >99%. Potent, selective ERβ agonist (EC₅₀ values are 0.85 and 66 nM for ERβ and ERα, respectively). Cardioprotective and neuroprotective in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cellular Antioxidant Assay Kit
Cellular Antioxidant Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sulforhodamine 101 acid chloride, amine-reactive rhodamine dye, 5MG
MW 625.2 Da, Purity >95%. Long wavelength red fluorescent amine-reactive rhodamine dye, also known as Texas Red. Useful for histological staining as well as in cell sorting experiments with fluorescent-activated cell sorting machines (FACS).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Metronidazole, Antiparasitic and antibacterial compound, 25G
MW 171.15 Da, Purity >99%. Nitroimidazole compound with antiparasitic and antibacterial activity. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Diallyl tetrasulfide, ROS inducer, 100MG
MW 210.4 Da, Purity >90%. JNK activator. ROS inducer. Irreversible Cdc25 isoforms A and C inhibitor. Targets tubulin. Induces G2-M arrest and apoptosis. Shows antiproliferative, cytoprotective and antioxidant effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Phortress, Antitumor agent, 50MG
MW 459.4 Da, Purity >98%. Potent antitumor agent (IC₅₀ values for MCF-7 and MDA468 cells are 40 nM and 158 nM, respectively). Active against breast, ovarian and renal carcinomas. Taken up into sensitive cells followed by aryl hydrocarbon receptor binding and translocation into the nucleus. Requires metabolic activation by cytochrome P450 to generate cytotoxic species. Active in vitro and in vivo. Water soluble.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human BD-3 peptide, 100UG
Human BD-3 peptide is a Synthetic blocking peptide. >95% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: BD3, DEFB103, DEFB3, DEFB103B, DEFB103A, Beta-defensin 103, Beta-defensin 3, Defensin-like protein, BD-3, DEFB-3, HBD3, hBD-3
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement